gi_545778205_gb_U000_141

cmsearch-Rfam

Family :

mir-192

Id:

RF00130

Type:

Gene; miRNA;

Taxonomy:

Eukaryota;

Ontology:

GO:0035195 gene silencing by miRNARF00130

Description:

This family represents the human microRNA (miRNA) precursors mir-192 and mir-215. Animal miRNAs are transcribed as
~70nt precursors and subsequently processed by the Dicer enzyme to give a ~22nt product. In
this case the mature sequence comes from the 5' arm of the precursor. The extents
of the hairpin precursors are not generally known and are estimated based on hairpin prediction.
The products are thought to have regulatory roles through complementarity to mRNA. The involvement of
Dicer in miRNA processing suggests a relationship with the phenomenon of RNA interference. miRNAs are
numbered based on the sequence of the mature RNA.

Score:

32.2

E-value:

3.7e-05

From sequence:

4171833

To sequence:

4171732

Alignments:

                                  v           v          vvvv              v              v               vvvv   NC
                               :::<<<-------<-<<<------<<<<<<<-<<<<<<<<<<<<<<____________>>>>>>>>>>>>>>-->>>>>>> CS
               RF00130       1 auucaGAaaugGUguaCAGGaaaaUGaCCUAUgAAuUGaCAGcCAgUguuuuuaaacUcUGgCUGuCAaUUcUgUAGGcCA 81     
                                U  :GA A  GU + C:G  AAA::AC+ AU:AA::GA AG:C : GU UUU  ACU: G:CU UC::UU:  U    ::
  gi_545778205_gb_U000 4171833 CUCAGGAGAGCGUUCACCGACAAACAACAGAUAAAACGAAAGGCCCAGUCUUUCGACUGAGCCUUUCGUUUUAUU----UG 4171757
                               **********************************************************************99886....89 PP

                                       v      v          NC
                               ------>>>->-->>>::::::::: CS
               RF00130      82 auauUcUGuacguCuguauuaCuuc 106    
                               AU+   :G A  UC: UA+U+   C
  gi_545778205_gb_U000 4171756 AUGCCUGGCAGUUCCCUACUCUCGC 4171732
                               ************************* PP

RNAfold
>gi_545778205_gb_U000_141
UGCGAGAGUAGGGAACUGCCAGGCAUCAAAUAAAACGAAAGGCUCAGUCG
AAAGACUGGGCCUUUCGUUUUAUCUGUUGUUUGUCGGUGAACGCUCUCCU
GAGUA
...((((((.(...((((.((((((.((.((((((((((((((((((((....)))))))))))))))))))).)).)))))).))))...)))))))....... (-53.30)

Length sequence

: 105

Length match:

100