gi_545778205_gb_U000_35

cmsearch-Rfam

Family :

CPEB3_ribozyme

Id:

RF00622

Type:

Gene; ribozyme;

Taxonomy:

Eukaryota;

Ontology:

Not found

Description:

The mammalian CPEB3 ribozyme is a self cleaving RNA located in the second intron of the
CPEB3 gene which belongs to a family of genes regulating messenger RNA polyadenylation [1]. This
ribozyme is highly conserved and found only in mammals [1]. The CPEB3 ribozyme is structurally
and biochemically related to the human hepatitis delta virus (HDV) ribozyme (Rfam:RF00094) and the HDV
ribozyme is proposed to have arisen from the human transcriptome [1]. There is currently only
one other known self cleaving ribozyme in mammals, the CoTC motif (Rfam:RF00621)[2].

Score:

22.1

E-value:

0.003

From sequence:

258828

To sequence:

258936

Alignments:

                                              v                          v       v                v            NC
                              ::::::::::::<<<<<----------<<<___~~~~~~>>>->>>>>---<<<<<<<____>>>>>>>::::::::::: CS
               RF00622      1 AGaGgAuAacagGGGGCCAcaGcAGAAGCGUUC*[ 4]*CGCGGCCCCUGUCAGAUUCugGuGAAUCUGCGAAUUCUGCu 78    
                               G      A AG::GG  AC+G A  AG:GUUC      C:C  CC:: GU AG UUC+ G GAA CU CG    CUGCU
  gi_545778205_gb_U000 258828 UGUUCGAUAAAGCAGGCGACUGGAAGAGUGUUC*[35]*CACACCCUGCGUGAGUUUCACGAGAAGCUGCGUGAACUGCU 258936
                              *******************************98...*..***************************************** PP

RNAfold

>gi_545778205_gb_U000_35
GUUCGAUAAAGCAGGCGACUGGAAGAGUGUUCCGGUAAAAGACACUGAAG
UGGUUGAACGACUGGAGCACACCCUGCGUGAGUUUCACGAGAAGCUGCGU
GAACUGCU
.........((((((((.(.((....((((((((((....(((.(......)))).....))))))))))..)).))))....((((((........))))))))))) (-30.60)

Length sequence

: 108

Length match:

107