Ec_micF,

cmscan-Rfam

Family :

MicF

Id:

RF00033

Type:

Gene; antisense;

Taxonomy:

Eukaryota; Bacteria;

Ontology:

GO:0006950 response to stressRF00033

Description:

The micF gene is a stress response gene found in Escherichia coli and related bacteria that
post-transcriptionally controls expression of the outer membrane porin gene ompF. The micF gene encodes a
non-translated 93 nt antisense RNA that binds its target ompF mRNA and regulates ompF expression
by inhibiting translation and inducing degradation of the message. In addition, other factors, such as
the RNA chaperone protein StpA also play a role in this regulatory system. Expression of
micF is controlled by both environmental and internal stress factors. Four transcriptional regulators are known
to bind the micF promoter region and activate micF expression.

Score:

114.1

E-value:

7.5e-20

From sequence:

81

To sequence:

174

Alignments:

                                                    v  v                                                      NC
               ::::::::::::::::::::::::::::::::<<<<<<__>>>>>>-------------------<<<<<<<<<<___>>>>>>>>>>:::::: CS
   RF00033   1 CGCUAUCAUCAUUAacUUuAUUUAUUACCgUCAUUcaguucugAAUgUCUGuuUACCCCUAUUUcaAcCGgaugCUUCGcaucCGgUuUUUUuu 94 
               CGCUAUCAUCAUUAACUUUAUUUAUUACCGUCAUUCA UU UGAAUGUCUGUUUACCCCUAUUUCAACCG:AUGC UCGCAU:CGGUUUUUUUU
  Ec_micF,  81 CGCUAUCAUCAUUAACUUUAUUUAUUACCGUCAUUCAUUUCUGAAUGUCUGUUUACCCCUAUUUCAACCGGAUGCCUCGCAUUCGGUUUUUUUU 174
               ********************************************************************************************** PP

RNAfold
>Ec_micF,
gcuaucaucauuaacuuuauuuauuaccgucauucauuucugaaugucug
uuuaccccuauuucaaccggaugccucgcauucgguuuuuuuu
.........................((.(.((((((....)))))).).)).............((((((((((...))))))))))...... (-18.90)

Length sequence

: 93

Length match:

92